March 26, 2019

This new paper identify a key brain network responsible for alcohol dependence and demonstrates that it is possible to reverse the desire to drink in alcohol-dependent rats by targeting this specific group of neurons using lasers.

In a new study published...

October 17, 2018

The George lab demonstrates that a novel enzymatic approach that prevents nicotine from reaching the brain not only decrease the level of nicotine dependence, but also decreases compulsive nicotine intake and relapse in animal models.

In a study published online in Scie...

January 9, 2018

The George lab published a new study in collaboration with the Janda lab providing preclinical evidence that a newly engineered enzyme can degrade nicotine in the blood so that nicotine cannot reach the brain and produce dependency effects.

This preclinical st...

August 26, 2017

The George lab published a new study providing preclinical evidence that several months of alcohol binge-like drinking facilitates the transition to compulsive-like alcohol drinking, but that regular drinking ultimately leads to similar level of compulsive drinking.

Thi...

May 27, 2017

The George lab published a new invited review in collaboration with Dr. Bruce Hope at the National Institute on Drugs of Abuse (NIDA) on the identification of specific neuronal ensembles responsible for different aspects of alcohol use disorder.

This review is part of a...

April 11, 2017

The George lab published a new study providing preclinical evidence that self-administration of alcohol vapor produces alcohol dependence in rats.

This preclinical study lead by Dr. de Guglielmo (Senior Research Associate in the George lab) demonstrates voluntary induct...

September 16, 2016

Tune in to Reddit.com/r/science today 2-4PM (PST) for an "Ask Me Anything" session with Dr. Olivier George

July 29, 2015

Increasing awareness of the dramatic impact of drug addiction on our society and providing novel therapeutic approaches to cure drug addiction are key missions of TSRI researchers in the George lab.

 

LA JOLLA, CA – July 29 2015 – Nature Outlook: Addiction is a very int...

July 6, 2015

A new paper published in collaboration with Leandro Vendruscolo and the Barbara Mason lab provide robust evidence that mifepristone reduces alcohol drinking in rats and humans.

 

LA JOLLA, CA – April 21, 2015 – The present studies indicate that attenuation of GR function...

April 22, 2015

Addiction research laboratory: Olivier George, scripps research institute, californiaUMMS/TSRI Researchers Discover New Neuronal Pathway Responsible for Anxiety During Nicotine Withdrawal

 

LA JOLLA, CA – April 21, 2015 – Few months ago we published a paper in Nature Neuroscience providing evidence that a previously unknown population of corticotropin re...

April 14, 2015

Addiction research laboratory: Olivier George, scripps research institute, californiaTSRI Researchers Discover Neuronal Network Behind the Facilitating Effect of Nicotine on Alcohol Dependence

 

LA JOLLA, CA – March 11, 2015 – Why do smokers have a five to ten times greater risk of developing alcohol dependence than nonsmokers? Do smokers have a greater...

November 17, 2014

TSRI Researchers Discover New Type of Neuron that Plays Key Role in Nicotine Addiction

LA JOLLA, CA – November 17, 2014 – For decades, scientists thought drug addiction was the result of two separate systems in the brain—the reward system, which was activated when a per...

August 15, 2014

A postdoctoral position will be available in the lab in a near future:

  • Succesful applicants will receive training under support from the NIH/NIAAA T32 Training grant program (US citizen/permanent residents).

  • This solicitation seeks applicants who have interest...

August 4, 2014

Latest paper published: Nicotine dependence increases the number of immature neurons in the hippocampus.

 

It was believed that nicotine and tobacco smoke decrease the production of new neurons in adult. However, previous studies have  used animal models with limited rel...

April 24, 2014

The lab has just been awarded a new 5 year grant by the NIH to study Alcohol Vapor Self-Administration. Very excited to start this new line of research.

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Upcoming Events

Research Society on Alcoholism

Dr. Kimbrough will be speaking. "Brain wide neural activation in animal models of alcohol abuse and dependence"

June 22-26th, 2019

Minneapolis, Minnesota

NeuroHIV Emerging Issues and Substance Abuse Joint Colloquium Nov 22-24th 2018

Dr. George will be speaking on "Identification of novel targets for cocaine and opioid use disorders using heterogeneous stock rats."

Outreach: Science Saturday Nov 17th 2018

Dr. George will be speaking on “Drug Wars: Episode IV – A New Hope”

Finding new therapies to fight drug addiction: The lecture will describe the effects of drugs on the brain, including alcohol, nicotine, cocaine and opioids; why some people, but not others, develop an addiction; and highlight new therapeutic strategies to fight addiction.

Scripps Research scientists and researchers bring the excitement and passion of research to middle and high school students. Every lecture highlights the cutting-edge research occurring at The Scripps Research Institute and provides a window into the life of a scientist.

"Drug Addiction & Mental Disorders" & "Impulse Control Disorders"

Dr. George is teaching PSYC 179 and PSYC188 at UCSD in Summer and Fall 2018

Summer and Fall 2018

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Pilot Grants Available to use the Cocaine and Oxycodone Biobanks

June 5, 2019

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