March 26, 2019

This new paper identify a key brain network responsible for alcohol dependence and demonstrates that it is possible to reverse the desire to drink in alcohol-dependent rats by targeting this specific group of neurons using lasers.

In a new study published...

October 17, 2018

The George lab demonstrates that a novel enzymatic approach that prevents nicotine from reaching the brain not only decrease the level of nicotine dependence, but also decreases compulsive nicotine intake and relapse in animal models.

In a study published online in Scie...

October 14, 2018

The George lab identified the orphan receptor GPR139 as a potential target for the treatment of compulsive alcohol drinking and hyperalgesia during alcohol withdrawal.

This study, lead by Dr. Jenni Kononoff provides 

robust preclinical evide...

July 5, 2018

The George lab, in collaboration with multiple research groups, published several studies that identify key brain mechanisms responsible for drug and nicotine addiction.

These studies 1) provide robust preclinical evidence fort the efficacy of deep brain stimu...

July 5, 2018

Dr. de Guglielmo from the George lab published a new study in collaboration with the Palmer lab (UCSD) that provide robust preclinical evidence that a novel compound called pBBG is more effective in reducing alcohol intake in dependent rats than in nondepende...

July 2, 2018

Dr. George published a new review article in collaboration with Dr. Koob that argues that characterization of the neuropsychological mechanisms that underlie individual differences in addiction-like behaviors is the key to understanding the mechanisms of addiction and...

January 9, 2018

The George lab published a new study in collaboration with the Janda lab providing preclinical evidence that a newly engineered enzyme can degrade nicotine in the blood so that nicotine cannot reach the brain and produce dependency effects.

This preclinical st...

July 29, 2015

Increasing awareness of the dramatic impact of drug addiction on our society and providing novel therapeutic approaches to cure drug addiction are key missions of TSRI researchers in the George lab.

 

LA JOLLA, CA – July 29 2015 – Nature Outlook: Addiction is a very int...

July 6, 2015

A new paper published in collaboration with Leandro Vendruscolo and the Barbara Mason lab provide robust evidence that mifepristone reduces alcohol drinking in rats and humans.

 

LA JOLLA, CA – April 21, 2015 – The present studies indicate that attenuation of GR function...

April 22, 2015

Addiction research laboratory: Olivier George, scripps research institute, californiaUMMS/TSRI Researchers Discover New Neuronal Pathway Responsible for Anxiety During Nicotine Withdrawal

 

LA JOLLA, CA – April 21, 2015 – Few months ago we published a paper in Nature Neuroscience providing evidence that a previously unknown population of corticotropin re...

April 14, 2015

Addiction research laboratory: Olivier George, scripps research institute, californiaTSRI Researchers Discover Neuronal Network Behind the Facilitating Effect of Nicotine on Alcohol Dependence

 

LA JOLLA, CA – March 11, 2015 – Why do smokers have a five to ten times greater risk of developing alcohol dependence than nonsmokers? Do smokers have a greater...

March 12, 2015

TSRI Researchers Discover New Mechanism that Plays Key Role in Methamphetamine Addiction

 

LA JOLLA, CA – March 11, 2015 – Methamphetamine abuse and dependence is a major issue in the US. More than 1 million people used methamphetamine in the past year and its use is ass...

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Upcoming Events

Research Society on Alcoholism

Dr. Kimbrough will be speaking. "Brain wide neural activation in animal models of alcohol abuse and dependence"

June 22-26th, 2019

Minneapolis, Minnesota

NeuroHIV Emerging Issues and Substance Abuse Joint Colloquium Nov 22-24th 2018

Dr. George will be speaking on "Identification of novel targets for cocaine and opioid use disorders using heterogeneous stock rats."

Outreach: Science Saturday Nov 17th 2018

Dr. George will be speaking on “Drug Wars: Episode IV – A New Hope”

Finding new therapies to fight drug addiction: The lecture will describe the effects of drugs on the brain, including alcohol, nicotine, cocaine and opioids; why some people, but not others, develop an addiction; and highlight new therapeutic strategies to fight addiction.

Scripps Research scientists and researchers bring the excitement and passion of research to middle and high school students. Every lecture highlights the cutting-edge research occurring at The Scripps Research Institute and provides a window into the life of a scientist.

"Drug Addiction & Mental Disorders" & "Impulse Control Disorders"

Dr. George is teaching PSYC 179 and PSYC188 at UCSD in Summer and Fall 2018

Summer and Fall 2018

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Featured Posts

Pilot Grants Available to use the Cocaine and Oxycodone Biobanks

June 5, 2019

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