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Building a brain map of alcohol dependence.
This new paper provide the first brain map of alcohol dependence at single cell resolution in an animal model of Alcohol use disorder....
Olivier George
3 min read


Treating opioid use disorder one rat at a time.
This paper provide preclinical evidence that targeting the D3 receptors may provide efficacy in the treatment of opioid use disorder....
Olivier George
1 min read


Identification of a new target that reduces excessive opioid use in dependent individuals.
This new paper identify a neuropeptide that is acting in a key brain region responsible for opioid dependence and demonstrates that it is...
Olivier George
2 min read


Identification of a neuronal pathway responsible for excessive drinking and alcohol dependence
This new paper identify a key brain network responsible for alcohol dependence and demonstrates that it is possible to reverse the desire...
Olivier George
3 min read


An Enzymatic Approach for the Treatment of Nicotine Addiction
The George lab demonstrates that a novel enzymatic approach that prevents nicotine from reaching the brain not only decrease the level of...
Olivier George
4 min read


Identification of an Orphan Receptor as Novel Molecular Target for Alcohol Dependence.
The George lab identified the orphan receptor GPR139 as a potential target for the treatment of compulsive alcohol drinking and...
Olivier George
3 min read


Identification of the cellular mechanisms of drug and nicotine addiction.
The George lab, in collaboration with multiple research groups, published several studies that identify key brain mechanisms responsible...
Olivier George
2 min read


A novel target for the treatment of alcohol use disorder.
Dr. de Guglielmo from the George lab published a new study in collaboration with the Palmer lab (UCSD) that provide robust preclinical...
Olivier George
1 min read


An enzymatic advance in nicotine cessation therapy.
The George lab published a new study in collaboration with the Janda lab providing preclinical evidence that a newly engineered enzyme...
Olivier George
1 min read


Alcohol binge-drinking facilitates the transition to dependence, but regular drinking may be almost
The George lab published a new study providing preclinical evidence that several months of alcohol binge-like drinking facilitates the...
Olivier George
2 min read


Cortical and Amygdalar Neuronal Ensembles in Alcohol Seeking, Drinking and Withdrawal
The George lab published a new invited review in collaboration with Dr. Bruce Hope at the National Institute on Drugs of Abuse (NIDA) on...
Olivier George
1 min read


Voluntary vaping alcohol produces alcohol dependence in rats.
The George lab published a new study providing preclinical evidence that self-administration of alcohol vapor produces alcohol dependence...
Olivier George
3 min read


New paper published: Nicotine facilitates the transition to alcohol dependence through dysfunction o
LA JOLLA, CA – March 11, 2015 – Why do smokers have a five to ten times greater risk of developing alcohol dependence than nonsmokers? Do...
Olivier George
3 min read


New paper published: Finding new ways to treat methamphetamine dependence.
LA JOLLA, CA – March 11, 2015 – Methamphetamine abuse and dependence is a major issue in the US. More than 1 million people used...
Olivier George
3 min read


New paper published by the George Lab: Identification of a new type of neurons that contributes to n
TSRI Researchers Discover New Type of Neuron that Plays Key Role in Nicotine Addiction LA JOLLA, CA – November 17, 2014 – For decades,...
Olivier George
4 min read


Postdoctoral position available in the lab UPDATE: position has been filled.
A postdoctoral position will be available in the lab in a near future: Succesful applicants will receive training under support from the...
Olivier George
1 min read


Smoking may produce excessive immature neurons
Latest paper published: Nicotine dependence increases the number of immature neurons in the hippocampus. It was believed that nicotine...
Olivier George
1 min read


Characterization of HIV rats
Latest paper published: A neuroanatomical, genetical, and cognitive characterization of HIV rats. This paper (link to PDF) validates the...
Olivier George
1 min read
How rats order a Martini
This video shows how rats vocalize in anticipation of access to alcohol. They produce sounds that the human ear can't process, but if you...
Olivier George
1 min read


Decreased, not increased phasic dopamine release predict cocaine dependence
This is to me one of the most important paper of the decade in the addiction field. It kicks to the curb both the incentive sensitization...
Olivier George
1 min read
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