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Olivier George
- Jan 14, 2020
- 3 min
Building a brain map of alcohol dependence.
This new paper provide the first brain map of alcohol dependence at single cell resolution in an animal model of Alcohol use disorder. Employing advanced technologies that allow whole brain imaging at single-cell resolution, researchers at University of California San Diego School of Medicine report that in an alcohol-dependent mouse model, the rodent brain’s functional architecture is substantially remodeled. But when deprived of alcohol, the mice displayed increased coordin
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Olivier George
- Jan 13, 2020
- 2 min
Identification of a new target that reduces excessive opioid use in dependent individuals.
This new paper identify a neuropeptide that is acting in a key brain region responsible for opioid dependence and demonstrates that it is possible to reverse the motivation to use opioids in opioid-dependent rats. More than 2 million individuals in the United States currently have a substance use disorder that is related to prescription opioid pain relievers. In a new study published online in PNSA on January 13, 2020, Drs. Kallupi and de Guglielmo used behavioral models, mol
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