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George Lab
Addiction Research Laboratory at UCSD
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Research Updates & Discoveries
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Building a brain map of alcohol dependence.
This new paper provide the first brain map of alcohol dependence at single cell resolution in an animal model of Alcohol use disorder....
Olivier George
3 min read
Treating opioid use disorder one rat at a time.
This paper provide preclinical evidence that targeting the D3 receptors may provide efficacy in the treatment of opioid use disorder....
Olivier George
1 min read
Identification of a new target that reduces excessive opioid use in dependent individuals.
This new paper identify a neuropeptide that is acting in a key brain region responsible for opioid dependence and demonstrates that it is...
Olivier George
2 min read
Identification of a neuronal pathway responsible for excessive drinking and alcohol dependence
This new paper identify a key brain network responsible for alcohol dependence and demonstrates that it is possible to reverse the desire...
Olivier George
3 min read
An Enzymatic Approach for the Treatment of Nicotine Addiction
The George lab demonstrates that a novel enzymatic approach that prevents nicotine from reaching the brain not only decrease the level of...
Olivier George
4 min read
Identification of an Orphan Receptor as Novel Molecular Target for Alcohol Dependence.
The George lab identified the orphan receptor GPR139 as a potential target for the treatment of compulsive alcohol drinking and...
Olivier George
3 min read
Identification of the cellular mechanisms of drug and nicotine addiction.
The George lab, in collaboration with multiple research groups, published several studies that identify key brain mechanisms responsible...
Olivier George
2 min read
A novel target for the treatment of alcohol use disorder.
Dr. de Guglielmo from the George lab published a new study in collaboration with the Palmer lab (UCSD) that provide robust preclinical...
Olivier George
1 min read
It is time to put the patient at the center of addiction treatments.
Dr. George published a new review article in collaboration with Dr. Koob that argues that characterization of the neuropsychological...
Olivier George
1 min read
An enzymatic advance in nicotine cessation therapy.
The George lab published a new study in collaboration with the Janda lab providing preclinical evidence that a newly engineered enzyme...
Olivier George
1 min read
Our work on nicotine dependence featured in Nature Outlook.
Increasing awareness of the dramatic impact of drug addiction on our society and providing novel therapeutic approaches to cure drug...
Olivier George
1 min read
A novel therapeutic strategy for alcoholism: Blocking the stress system using glucocorticoid antagon
A new paper published in collaboration with Leandro Vendruscolo and the Barbara Mason lab provide robust evidence that mifepristone...
Olivier George
1 min read
New paper published in collaboration with the Tapper lab: Identification of a new brain pathway cont
LA JOLLA, CA – April 21, 2015 – Few months ago we published a paper in Nature Neuroscience providing evidence that a previously unknown...
Olivier George
1 min read
New paper published: Nicotine facilitates the transition to alcohol dependence through dysfunction o
LA JOLLA, CA – March 11, 2015 – Why do smokers have a five to ten times greater risk of developing alcohol dependence than nonsmokers? Do...
Olivier George
3 min read
New paper published: Finding new ways to treat methamphetamine dependence.
LA JOLLA, CA – March 11, 2015 – Methamphetamine abuse and dependence is a major issue in the US. More than 1 million people used...
Olivier George
3 min read
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