When scientists study addiction, they face a frustrating problem: most research uses genetically similar lab rats that don't reflect the diversity we see in human populations. It's like trying to understand how a disease affects everyone by only studying one family. We knew we needed a better approach. The Research Question We wanted to create comprehensive resources that would help researchers understand why some individuals become addicted while others don't. More specifica

We've all heard that addiction affects people differently. But why do some individuals spiral into severe addiction while others can take or leave drugs? We investigated this question using an innovative approach with genetically diverse rats, and what we found challenges some common assumptions about addiction. The Research Question We wanted to understand whether individual differences in addiction-like behaviors predict how much a rat will choose drugs over other rewarding

A key aspect of treating drug abuse is understanding similarities and differences of how drugs of abuse affect the brain. The George Lab...

The George Lab published a new study investigating electronic cigarette use. The main goal of the study was to validate a new...

Our newest review, “Role of CRF in Alcohol and Nicotine Addiction” was recently published in a special collection on "The Role of...

Substance use disorders are complex. Genetics, environment, and exposure all play a role in drug use. Recently, there has been evidence...

This new paper provide the first brain map of alcohol dependence at single cell resolution in an animal model of Alcohol use disorder....

This paper provide preclinical evidence that targeting the D3 receptors may provide efficacy in the treatment of opioid use disorder....

This new paper identify a neuropeptide that is acting in a key brain region responsible for opioid dependence and demonstrates that it is...

Join us! Postdoc Position available, apply here Research Description: The George lab is seeking applicants for a postdoctoral position...