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First evidence of escalation of nicotine intake in rats


Neuropsychopharmacology. 2012 Aug;37(9):2153-60. doi: 10.1038/npp.2012.67. Epub 2012 May 2.

Robust escalation of nicotine intake with extended access to nicotine self-administration and intermittent periods of abstinence.

Cohen A, Koob GF, George O.

#addiction #animalmodel #nicotine #compulsivity #escalation

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