Search
Building a brain map of alcohol dependence.
This new paper provide the first brain map of alcohol dependence at single cell resolution in an animal model of Alcohol use disorder....
Olivier George
Jan 14, 20203 min read
Treating opioid use disorder one rat at a time.
This paper provide preclinical evidence that targeting the D3 receptors may provide efficacy in the treatment of opioid use disorder....
Olivier George
Jan 14, 20201 min read
Identification of a new target that reduces excessive opioid use in dependent individuals.
This new paper identify a neuropeptide that is acting in a key brain region responsible for opioid dependence and demonstrates that it is...
Olivier George
Jan 13, 20202 min read
Identification of a neuronal pathway responsible for excessive drinking and alcohol dependence
This new paper identify a key brain network responsible for alcohol dependence and demonstrates that it is possible to reverse the desire...
Olivier George
Mar 25, 20193 min read
An Enzymatic Approach for the Treatment of Nicotine Addiction
The George lab demonstrates that a novel enzymatic approach that prevents nicotine from reaching the brain not only decrease the level of...
Olivier George
Oct 17, 20184 min read
Identification of an Orphan Receptor as Novel Molecular Target for Alcohol Dependence.
The George lab identified the orphan receptor GPR139 as a potential target for the treatment of compulsive alcohol drinking and...
Olivier George
Oct 14, 20183 min read
Identification of the cellular mechanisms of drug and nicotine addiction.
The George lab, in collaboration with multiple research groups, published several studies that identify key brain mechanisms responsible...
Olivier George
Jul 5, 20182 min read
A novel target for the treatment of alcohol use disorder.
Dr. de Guglielmo from the George lab published a new study in collaboration with the Palmer lab (UCSD) that provide robust preclinical...
Olivier George
Jul 5, 20181 min read
An enzymatic advance in nicotine cessation therapy.
The George lab published a new study in collaboration with the Janda lab providing preclinical evidence that a newly engineered enzyme...
Olivier George
Jan 9, 20181 min read
Alcohol binge-drinking facilitates the transition to dependence, but regular drinking may be almost
The George lab published a new study providing preclinical evidence that several months of alcohol binge-like drinking facilitates the...
Olivier George
Aug 25, 20172 min read
Cortical and Amygdalar Neuronal Ensembles in Alcohol Seeking, Drinking and Withdrawal
The George lab published a new invited review in collaboration with Dr. Bruce Hope at the National Institute on Drugs of Abuse (NIDA) on...
Olivier George
May 27, 20171 min read
Voluntary vaping alcohol produces alcohol dependence in rats.
The George lab published a new study providing preclinical evidence that self-administration of alcohol vapor produces alcohol dependence...
Olivier George
Apr 11, 20173 min read
Deep brain stimulation reduces the compulsion to take heroin.
The George lab published a novel study providing preclinical evidence that deep brain stimulation can decrease the motivation for heroin...
Olivier George
Feb 1, 20171 min read