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RESEARCH APPROACHES

We use a multilevel integrated approach to identify the biological mechanisms underlying addiction

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Addiction-like behaviors

Alcohol, nicotine, drug self-administration

Oral, intravenous, subcutaneous, vapor exposure

Negative emotional states

Analgesia, hyperalgesia, and more...

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Untarget/targeted

Metabolomic

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Proof of concept studies

PK/PD

Dose-response

Chronic studies

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Neuroanatomy

Functional connectomics

Optogenetics

Chemogenetics

Deep brain stimulation

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Ex-vivo slice electrophysiology ​

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16s RNAseq

Qiime2

PICRUSt2

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scRNAseq

Spatial Transcriptomic

Hover over images to view some of the techniques used
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