Dynorphin system and heroin escalationOlivier GeorgeDec 14, 20131 min read Long-term antagonism of kappa opioid receptors preventsescalation of and increased motivation for heroin intake. Journal of Neuroscience. in press Schlosburg J, Whitfield T, Park P, Crawford E, George O, Vendruscolo L, and Koob GF#heroin #dynorphin #stress #accumbens #kappa #craving
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