Olivier GeorgeDec 14, 20131 min readDynorphin system and heroin escalation Long-term antagonism of kappa opioid receptors preventsescalation of and increased motivation for heroin intake. Journal of Neuroscience. in press Schlosburg J, Whitfield T, Park P, Crawford E, George O, Vendruscolo L, and Koob GF#heroin #dynorphin #stress #accumbens #kappa #craving
Long-term antagonism of kappa opioid receptors preventsescalation of and increased motivation for heroin intake. Journal of Neuroscience. in press Schlosburg J, Whitfield T, Park P, Crawford E, George O, Vendruscolo L, and Koob GF#heroin #dynorphin #stress #accumbens #kappa #craving