Increasing awareness of the dramatic impact of drug addiction on our society and providing novel therapeutic approaches to cure drug...

A new paper published in collaboration with Leandro Vendruscolo and the Barbara Mason lab provide robust evidence that mifepristone...

Long-term antagonism of kappa opioid receptors preventsescalation of and increased motivation for heroin intake. Journal of Neuroscience....

Extended access to nicotine leads to a CRF1 receptor dependent increase in anxiety-like behavior and hyperalgesia in rats. Addiction...

Addiction as a stress surfeit disorder ​Neuropharmacology. 2013 Jun 6 Koob GF, Buck CL, Cohen A, Edwards S, Park PE, Schlosburg JE,...

Control of craving by the prefrontal cortex ​PNAS. 2013 Mar 12; 110(11):4165-6: George O and Koob GF #prefrontalcortex #addiction...