Increasing awareness of the dramatic impact of drug addiction on our society and providing novel therapeutic approaches to cure drug...

A new paper published in collaboration with Leandro Vendruscolo and the Barbara Mason lab provide robust evidence that mifepristone...

LA JOLLA, CA – March 11, 2015 – Why do smokers have a five to ten times greater risk of developing alcohol dependence than nonsmokers? Do...

LA JOLLA, CA – March 11, 2015 – Methamphetamine abuse and dependence is a major issue in the US. More than 1 million people used...

Long-term antagonism of kappa opioid receptors preventsescalation of and increased motivation for heroin intake. Journal of Neuroscience....

Extended access to nicotine leads to a CRF1 receptor dependent increase in anxiety-like behavior and hyperalgesia in rats. Addiction...

Addiction as a stress surfeit disorder ​Neuropharmacology. 2013 Jun 6 Koob GF, Buck CL, Cohen A, Edwards S, Park PE, Schlosburg JE,...