CRF, anxiety, pain and nicotine dependence
Extended access to nicotine leads to a CRF1 receptor dependent increase in anxiety-like behavior and hyperalgesia in rats.
Addiction Biology. 2013 Jul 22
Cohen A, Treweek J, Edwards S, Leão RM, Schulteis G, Koob GF, George O.
#addiction #craving #nicotine #escalation #crf #pain #anxiety #amygdala #stress
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